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Slider_guess

 

Slider_guess [...]

Allows one to enter a guess into the database. After getting a score, the user is asked if it should be associated with some coordinates. This allows one to first build a poly-alanine, for example, then later try to work out where one is in the sequence. Since one could have build the initial structure backwards, the program gives you the chance of associating the guess with a backwards model.

The `slider matrix' must have been loaded.  

  O >  sl_gues
 Slid>  There are    132 residues in molecule.
 Slid>  There is no slider matrix in the database.
  O >  read ../data/slider.o 
 Slid>  There are    132 residues in molecule.
 Slid> Estimated sequence:  gvwa 
 Slid>  Average=      0.43,rms=      0.14
 Slid>                       GVWA
 Slid>  Fit   1 0.875 A6     GTWK
 Slid>  Fit   2 0.725 A33    GNLA
 Slid>  Fit   3 0.700 A84    VTLA
 Slid>  Fit   4 0.675 A26    GLAT
 Slid>  Fit   5 0.675 A55    SPFK
 Slid>  Fit   6 0.675 A122   VVCT
 Slid>  Fit   7 0.650 A99    GNET
 Slid>  Fit   8 0.650 A82    STVT
 Slid>  Fit   9 0.650 A111   GKMV
 Slid>  Fit  10 0.625 A28    ATRK
 Slid>  Fit  11 0.625 A89    GSLN
 Slid>  Fit  12 0.600 A62    ISFK
 Slid>  Fit  13 0.600 A40    VIIS
 Slid>  Fit  14 0.600 A72    ETTA
 Slid>  Fit  15 0.600 A24    GVGL
 Slid>  Fit  16 0.600 A50    TIRT
 Slid>  Fit  17 0.600 A22    ALGV
 Slid>  Fit  18 0.575 A102   TTIK
 Slid>  Fit  19 0.550 A79    KTKS
 Slid>  Fit  20 0.550 A73    TTAD
 Slid> Do you want to associate with a residue ([Y],n)?
 Slid> Molecule and residue name :  a a6
 Slid> Forwards or backwards ([F],b)?

The best fitting sequence is now shown on the display, and a dial controls which of the fits is displayed. To accept it into the database, type

  O >  yes 
 Slid> What name to associate with guess? g1

The guess text can be 1-6 characters in length and creates 4 items in the database. Which can be retrieved by other commands

  O >  dir *g1* 
 Heap>  .SLIDER_XYZ_G1            R W        12
 Heap>  .SLIDER_SEQ_G1            T W         4
 Heap>  .SLIDER_POS_G1            I W       132
 Heap>  .SLIDER_FIT_G1            R W       132